eradicate coronavirus by blocking replication, counteracting its defense system
DATE: 31 March 2020
SIRT1 inhibitors can reduce replication of many viruses with certain similar characteristics to those of Coronaviruses, while p53 protein is another important factor in down-regulation of growth. There are some molecules that inhibit Sirtuin 1 and 2, in addition to activate p53 protein, by means of regulation of the interactions used by Coronaviruses as self-defense mechanism, degradating it. Even mTOR signal will be regulate, as well as HIF-1α with the target genes and cytokines. Autophagy will be inhibited, being this compound like a lysosomotropic agent. By blocking virus growth and continuous replication, associating the already tested Antiviral medicines, Covid-19 could be eradicated.
Coronavirus, Covid-19, Covid, Sars-Cov-2, Coronavirus replication, SIRT1 inhibitors, SIRT1, p53 mTOR, Autophagy
License (for files):
Smith, K., Dr. (2020, August 5). Eradicate Coronavirus by blocking replication, counteracting its defense system.
Smith, Kira, Dr. “Eradicate Coronavirus by Blocking Replication, Counteracting Its Defense System.” OSF Preprints, 5 Aug. 2020. Web.
Smith, Kira, Dr. 2020. “Eradicate Coronavirus by Blocking Replication, Counteracting Its Defense System.” OSF Preprints. August 5. doi:10.31219/osf.io/psz35.
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