Microscopio in laboratorio

Research

 

eradicate coronavirus by blocking replication, counteracting its defense system

DATE: 31 March 2020

 

ABSTRACT:

SIRT1 inhibitors can reduce replication of many viruses with certain similar characteristics to those of Coronaviruses, while p53 protein is another important factor in down-regulation of growth. There are some molecules that inhibit Sirtuin 1 and 2, in addition to activate p53 protein, by means of regulation of the interactions used by Coronaviruses as self-defense mechanism, degradating it. Even mTOR signal will be regulate, as well as HIF-1α with the target genes and cytokines. Autophagy will be inhibited, being this compound like a lysosomotropic agent. By blocking virus growth and continuous replication, associating the already tested Antiviral medicines, Covid-19 could be eradicated.

 

Keywords: 
Coronavirus, Covid-19, Covid, Sars-Cov-2, Coronavirus replication, SIRT1 inhibitors, SIRT1, p53 mTOR, Autophagy 

Lysosomotropic, HIF-1α, HIF, Cytokines, Cytokines Storm

 

License (for files):

Creative Commons Attribution 4.0 International

 

CITATION:

APA

Smith, K., Dr. (2020, August 5). Eradicate Coronavirus by blocking replication, counteracting its defense system. https://doi.org/10.31219/osf.io/psz35

 

MLA

Smith, Kira, Dr. “Eradicate Coronavirus by Blocking Replication, Counteracting Its Defense System.” OSF Preprints, 5 Aug. 2020. Web.

 

Chicago

Smith, Kira, Dr. 2020. “Eradicate Coronavirus by Blocking Replication, Counteracting Its Defense System.” OSF Preprints. August 5. doi:10.31219/osf.io/psz35.

Do you have any scientific material that you would like to see published, but don't know who to address to?

Send us your articles, we will evaluate them! 

Scienziato maschio

Send your researches!